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Rare-CSC - Historic collection of diverse, drug-like compounds. PDF Print E-mail

Historic collection of 20,400 diverse, primarily drug-like compounds is available for delivery.

TimTec presents a unique opportunity to access highly diverse and rare selection of some of the most interesting molecules by offering Historic Rare-CSC (HCSC), Rare--Compounds Screening Collection.

Rare--CSC reflects global diversity of chemical material and supply sources being a historic account of dynamic development of TimTec stock and market trends. The value of Rare-CSC is in unique chemistries and truly outstanding diversity in compounds selection that is largely drug-like.

Although over 40% of compounds in Rare-CSC are not currently available for immediate re-supply on the market, TimTec would provide 100% re-supply for individual compounds or entire Rare collection in different microliter aliquots for hit confirmation.

Rare-CSC gives a researcher an opportunity to work with rare chemical material that otherwise would be available only via virtual screening. 

Please contact us for more information and special offers for variety of formatting options.

Inquire Rare-CSC database on a CDRom

Compound Database CDROM

Drug-Like Porperties of the Rare-CSC - Historic collection of diverse, drug-like compounds

Distribution of Lipinski Number

Lipinski Rule of Five Definition: the Lipinski's Rule of Five states that an orally active drug should respect:
- a molecular weight under 500 Daltons
- a limited lipophilicity (expressed by cLogP < 5)
- max 5 H-bond donors (expressed as the sum of OHs and NHs)
- max 10 H-bond acceptors (expressed as the sum of Os and Ns).

Lipinski Rule of 5 for Rare-CSC 

Distribution of LogP
LogP Definitions: LogP is the octanol/water partition coefficient is the ratio of the solubility of a compound in octanol to its solubility in water)

Distribution of LogP

Distribution of Molecular Weight

Distribution of Molecular Weight 

Distribution of Hydrogen Bond Donors

Definition of Hydrigen Bond Donor: A hydrogen atom attached to a relatively electronegative atom is a hydrogen bond donor. This electronegative atom is usually fluorine, oxygen, or nitrogen.

Distribution of Hydrogen Donors 

Distribution of Hydrogen Bond Acceptors

Definition of Hydrigen Bond Acceptor: A chemical bond in which a hydrogen atom of one molecule is attracted to an electronegative atom, especially a nitrogen, oxygen, or fluorine atom, usually of another molecule.

Distribution of Hydrogen Acceptors  

 
info@timtec.net Harmony Business Park Building 301-A Newark, DE 19711
Toll free 800-574-7391 T: 302-292-8500  F: 302-292-8520
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