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| Template-Based |
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Template-based
libraries consist of groups with common heterocyclic
lattices |
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Phone:1-302-292-8500 Fax
302-292-8520
Email
info@timtec.net
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Template-Based Compound Libraries
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Groups of compounds by molecular
fragments that allow library selection
based on the relevance of this lattice
to lead discovery exploitation or
diversity augmentation.
The following table indicates the
appropriate number of compounds containing the
designated heterocycle that are
available from our stock library (2-4
week delivery).
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Compound
Types By Heterocycle Template
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Compound
Template
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Stock
Available
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5-Membered
Aromatic Heterocycles
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Total
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Pyrroles
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>4000
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Furans
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>7000
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Thiophenes
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>9000
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Imidazoles
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>5000
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Pyrazoles
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>5000
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Oxazoles
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>1500
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Isoxazoles
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>400
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Thiazoles
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>5000
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Isothiazoles
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>400
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Triazoles-1.2,4
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>2500
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Triazoles-1,2,3
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>1000
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Oxadiazoles-1,2,5
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>1500
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Oxadiazoles-1,3,4
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>300
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Oxadiazoles-1.2.4
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>175
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Thiadiazoles-1,3.4
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>1000
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Thiadiazoles-1,2,5
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>150
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Thiadiazoles-1,2,4
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25
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Tetrazoles
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>1000
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5-Membered
Fused Aromatic Heterocycles
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Total
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Indoles and
carbazoles
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>3000
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Phthalimides
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>2000
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Isatines
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51
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Benzofurans
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>800
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Benzothiophenes
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>300
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Benzimidazoles
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>2500
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Benzopyrazoles
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~100
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Benzoxazoles
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>1500
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Benzothiazoles
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>2500
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Benzotriazoles
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>400
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Purines
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~150
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6-Membered
Aromatic Heterocycles
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Total
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Pyridines
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>10,000
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Pyrimidines
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>3000
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Pyrazines
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>500
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Pyridazines
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>300
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Triazines-1,3,5
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>1800
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Triazines-1,2,4
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>500
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6-Membered
Fused Aromatic Heterocycles
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Total
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Quinolines
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>2000
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Quinazolines
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>200
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Quinoxalines
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>300
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Phthalazines
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>200
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